Selank5mg–10mg
$55Lyophilized Selank supplied as a research reference standard.
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Example Certificate of Analysis
Certificate of Analysis
Selank
Lot Number
EXAMPLE-LOT
Purity (HPLC)
≥99%
Nominal Fill
5mg
Illustrative example of the certificate format issued for this compound. Purity and specification figures are the published values for Selank; the lot number and test date are placeholders, not a real result. The certificate for the specific lot you receive is matched to the lot number printed on the vial. For laboratory research use only.
Characteristics
| Molecular Formula | C₃₃H₅₇N₁₁O₉ |
|---|---|
| CAS Number | 129954-34-3 |
| Molar Mass | 751.87 g/mol |
| Amino Acid Sequence | Thr-Lys-Pro-Arg-Pro-Gly-Pro |
| Synonyms | Selank, TP-7, Selanc |
| Physical Form | Lyophilized powder |
| Solubility | Soluble in water and physiological saline |
| Organoleptic Profile | White lyophilized powder; odorless |
| Purity | ≥98% by HPLC |
| Storage Conditions | Store lyophilized at -20°C; reconstituted solution stable at 2-8°C for up to 10 days |
How is Selank used in research?
Selank is a synthetic heptapeptide developed at the Institute of Molecular Genetics of the Russian Academy of Sciences. It is a structural analog of tuftsin (Thr-Lys-Pro-Arg), a naturally occurring immunostimulatory tetrapeptide, with an added Pro-Gly-Pro sequence that enhances metabolic stability and extends the peptide's biological half-life. Selank has been the subject of extensive preclinical research for its effects on anxiety-behavior research models, cognitive-function research markers, and immune-modulation markers.
The anxiolytic-assay mechanism of Selank is believed to involve modulation of GABAergic neurotransmission and influence on brain-derived neurotrophic factor (BDNF) expression. Research has demonstrated that Selank increases BDNF mRNA expression in the hippocampus and affects the balance of enkephalin and monoamine neurotransmitter systems. Unlike classical benzodiazepine anxiolytics, Selank does not appear to produce sedation, amnesia, or dependence in preclinical models, suggesting a distinct pharmacological profile.
Beyond its neurotropic effects, Selank retains immunomodulatory properties derived from its tuftsin backbone. Studies have shown that it can enhance the functional activity of phagocytes, modulate cytokine-marker expression, and influence the innate-immune response in preclinical systems. This dual action on both the nervous and immune systems has generated research interest in preclinical models where neuroinflammation markers and immune dysregulation intersect.
Areas of Study
Anxiolytic Research
Investigated as a non-sedating anxiolytic with a mechanism distinct from benzodiazepines, lacking sedation, amnesia, and dependence in preclinical models.
Nootropic & Cognitive Enhancement
Studied for effects on learning, memory consolidation, and attention through modulation of monoamine and enkephalin systems.
Immunomodulatory Activity
Retains tuftsin-derived immunostimulatory properties including enhancement of phagocyte activity and cytokine modulation.
GABAergic Neurotransmission
Research indicates modulation of GABA receptor signaling contributing to anxiolytic effects without typical benzodiazepine side effects.
BDNF Expression
Demonstrated upregulation of brain-derived neurotrophic factor mRNA in hippocampal regions relevant to mood and cognition.
References
- [1]Kozlovskii II, Danchev ND, Seredenin SB. (2003). Psychopharmacological profile of selank and its analogs. Bulletin of Experimental Biology and Medicine, 136(1), 53-55.
- [2]Seredenin SB, Kozlovskaya MM, Blednov YA, et al. (1998). Anxiolytic action of the synthetic peptide selank. Bulletin of Experimental Biology and Medicine, 125(5), 456-459.
- [3]Zozulya AA, Gabaeva MV, Sokolov OY, et al. (2001). Personality, coping style, and humoral immune response following selank administration. Regulatory Peptides, 101(1-3), 125-131.
- [4]Kozlovskii II, Danchev ND. (2003). The optimizing action of the synthetic peptide selank on a conditioned active avoidance reflex in rats. Neuroscience and Behavioral Physiology, 33(7), 639-643.
Disclaimer: Information provided for research reference only; not medical advice. Sold strictly for in-vitro research use.
Certificate of Analysis
Third-party verified
Every batch of Selank is independently tested by an A2LA-accredited (ISO 17025:2017) laboratory using HPLC-UV/VIS for purity and identity, with a batch-specific lot number. Results are published publicly.
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Frequently
Asked
Questions
Everything on purity, paperwork, shipping and the research-use-only terms. Still stuck? Read the full FAQ.
What does research use only mean?
Every compound we supply is a reference standard intended strictly for in-vitro laboratory research. It is not a drug or a supplement, and it is not for human or veterinary use, nor for diagnostic or therapeutic use.
How is purity verified?
Every lot is assayed by HPLC at an independent, accredited third-party laboratory. We publish the resulting Certificate of Analysis and link it to the lot number printed on the vial.
Where do I find the Certificate of Analysis?
Every lot has a public, batch-linked COA. Browse them all on the COA page, or open any product page and use the COA tab for that specific compound.
How quickly do orders ship?
Orders placed before 2PM EST ship the same business day. Shipments are cold-packed where required and fully tracked.
Do you ship internationally?
We currently ship within the United States. Requests from institutional buyers outside the US are handled case by case, so contact us before ordering.
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